Novel imidazopyrazines as cyclin dependent kinase inhibitors - Patent Pending

United States Patent Application 20050130980
Kind Code A1
Paruch, Kamil ; et al. June 16, 2005
Novel imidazopyrazines as cyclin dependent kinase inhibitors
Abstract
In its many embodiments, the present invention provides a novel class of imidazo[1,2-a]pyrazine compounds as inhibitors of cyclin dependent kinases, methods of preparing such compounds, pharmaceutical compositions containing one or more such compounds, methods of preparing pharmaceutical formulations comprising one or more such compounds, and methods of treatment, prevention, inhibition, or amelioration of one or more diseases associated with the CDKs using such compounds or pharmaceutical compositions.
Inventors: Paruch, Kamil; (Garwood, NJ) ; Guzi, Timothy J.; (Chatham, NJ) ; Dwyer, Michael P.; (Scotch Plains, NJ) ; Doll, Ronald J.; (Convent Station, NJ) ; Girijavallabhan, Viyyoor M.; (Parsippany, NJ) ; Mallams, Alan; (Hackettstown, NJ)
Correspondence Name and Address: SCHERING-PLOUGH CORPORATION
PATENT DEPARTMENT (K-6-1, 1990)
2000 GALLOPING HILL ROAD
KENILWORTH
NJ
07033-0530
US
Serial No.: 047524
Series Code: 11
Filed: January 31, 2005
U.S. Current Class: 514/249; 544/350
U.S. Class at Publication: 514/249; 544/350
Intern'l Class: A61K 031/498; C07D 487/04