Method of treating mammalian joint maladies by biological fluid transplantation

Method of treating mammalian joint maladies by biological fluid transplantation
US PATENT & TRADEMARK OFFICE
United States Patent Application 20060083787
Kind Code A1
Meader; Charles P. ; et al. April 20, 2006
Abstract
Disclosed is a product and method for transplanting biological fluids into a host animal (including humans) that have been collected from donor animals. These biological fluids have been purified and processed so that they are a cellular, sterile, pathogen free, and a form that can be stored for considerable periods of time without degradation. In one embodiment, synovial fluid is harvested from a large number of donors to produce the transplantation compound. Donor fluid is collected from a number of joints per animal, and initially screened for obvious abnormalities (clarity, color, viscosity. . . etc.) and accepted or rejected on a joint-by-joint basis at the time of collection. The collected fluid is frozen in the field. Once in a laboratory setting, the fluid is warmed and spun down in a centrifuge. The supernate is collected, filtered, and mixed in large batches while the permeate is discarded. The supernate is re-frozen, lyophilized (freeze-dried) to form a cake and packaged as an individual dose under vacuum. The product is sterile, stable, has a long shelf life and can be readily reconstituted and injected into a joint.
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Inventors: Meader; Charles P.; (Grover, CO) ; Christofferson; Paul V.; (Draper, UT)
Correspondence Name and Address: COCHRAN FREUND & YOUNG LLC
2026 CARIBOU DR
SUITE 200
FORT COLLINS
CO
80525
US

Serial No.: 727893
Series Code: 10
Filed: December 3, 2003
U.S. Current Class: 424/520
U.S. Class at Publication: 424/520
Intern'l Class: A61K 35/12 20060101 A61K035/12
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Comments: 0
Votes:22