Method for preparing porous composite material

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Patent Number: US2005004242
Publication date: 2005-01-06
Inventor(s): SOTOME SHINICHI [JP]; UEMURA TOSHIMASA [JP]; TANAKA JUNZO [JP]; KIKUCHI MASANORI [JP]; SHINOMIYA KENICHI [JP]; ITOH SOICHIRO [JP]; TATEISHI TETSUYA [JP]
Applicant(s):
Requested Patent: WO03092759
Application Number: US20040492300 20040412
Priority Number(s): WO2002JP04355 20020501
IPC Classification: C08J9/26
EC Classification: A61L24/00R4E, A61L27/44, A61L27/46, A61L27/56
Equivalents: EP1500405
Abstract
This invention relates to a process for producing porous and composite materials comprising steps of: freezing a complex containing at least one calcium salt selected from calcium carbonate, calcium phosphate, and hydroxyapatite and collagen, at least a part of which is gelatinized; and then lyophilizing the resultant. The porous and composite materials obtained by the method of the present invention have large pore diameters, high porosities, and adequate mechanical strengths and biodegradability. Thus, they are suitable for implants such as bone fillers, drug carriers for sustained-release, and the like.
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