METHODS FOR QUANTIFICATION OF MICRORNAS AND SMALL INTERFERING RNAS
METHODS FOR QUANTIFICATION OF MICRORNAS AND SMALL INTERFERING RNAS
Publication number: CA2562390
Publication date: 2005-10-20
Inventor: ECHWALD SOREN MORGENTHALER (DK); MOURITZEN PETER (DK); KAUPPINEN SAKARI (DK); KONGSBAK LARS (DK); JACOBSEN NANA (DK); NIELSEN PETER STEIN (DK); NORHOLM MIKKEL (DK)
Applicant: EXIQON AS (DK)
Classification:
- international: C12Q1/68; C12Q1/68;
- European: C12Q1/68D2C; C12Q1/68D2E
Application number: CA20052562390 20050407
Priority number(s): DK20040000578 20040407; DK20040001146 20040723; DK20040001218 20040811; DK20040001587 20041015; DK20050000140 20050128; WO2005DK00239 20050407
Abstract of CA2562390
The invention relates to ribonucleic acids, probes and methods for detection , quantification as well as monitoring the expression of mature microRNAs and small interfering RNAs (siRNAs). The invention furthermore relates to method s for monitoring the expression of other non-coding RNAs, mRNA splice variants , as well as detecting and quantifying RNA editing, allelic variants of single transcripts, mutations, deletions, or duplications of particular exons in transcripts, e.g., alterations associated with human disease such as cancer. The invention furthermore relates to methods for detection, quantification a s well as monitoring the expression of deoxy nucleic acids.
Votes:7
Comments: 0