METHOD OF MONITORING A FREEZE DRYING PROCESS

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Patent number: MXPA02010225
Publication date: 2003-04-25
Inventor: BRULLS ALVIN JOHAN MIKAEL (SE)
Applicant: ASTRAZENECA AB (SE)
Classification:
- international: 26B05/06A
- european:
Application number: MX2002PA10225 20021016
Priority number(s): WO2001GB01731 20010417; SE20000001453 20000419
Abstract of MXPA02010225

A method of monitoring a freeze drying process in an apparatus (1) holding one or more samples (9) of a material to be freeze dried, comprises the steps of directing input radiation onto the sample (9), the input radiation forming output radiation by interaction with the sample (9); collecting at least part of the output radiation and leading the thus collected radiation to a radiation analyzer (11); and analyzing the collected radiation spectroscopically in the radiation analyzer (11) to obtain a measurement value of one or more freeze drying parameters of the sample (9), such as the temperature of the sample (9) and or the content of a solvent in the sample (9) and or the structure of the sample (9).
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