Lyophilized composition of bone morphogenetic factor human MP52

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Patent Number: US2004132653
Publication date: 2004-07-08
Inventor(s): ICHIKAWA HIDEKI [JP]; INAGAKI MITSUKO [JP]
Applicant(s): BIOPHARM GMBH [DE]
Requested Patent: US2004132653
Application Number: US20030666535 20030922
Priority Number(s): US20030666535 20030922; JP19970016349 19970130; US19990355551 19990921
IPC Classification: A61K38/18
EC Classification: A61K9/19, A61K38/18H, A61K47/26
Equivalents:
Abstract
By mixing bone morphogenetic factor human MP52 with mannitol at a weight ratio of 1:5-50, followed by lyophilization, a stable lyophilized composition of bone morphogenetic factor human MP52 is obtained which prevents coloring and atrophy of the lyophilized product of bone morphogenetic factor human MP52 during storage and also prevents cohesion at the time of reconstitution.
Data supplied from the esp@cenet database - l2