LYOPHILIZED PREPARATION

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Patent Number: JP2004269401
Publication date: 2004-09-30
Inventor(s): SAWADA TAKASHI; MARUI MASANORI
Applicant(s): SAWAI PHARMACEUTICAL CO LTD
Requested Patent: JP2004269401
Application Number: JP20030061235 20030307
Priority Number(s):
IPC Classification: A61K31/546; A61K9/19; A61P31/04
EC Classification:
Equivalents:
Abstract
PROBLEM TO BE SOLVED: To obtain a lyophilized preparation having excellent stability of an amphoteric cephem-based antibiotic.
SOLUTION: The lyophilized preparation comprises the amphoteric cephem-based antibiotic and a halide ion selected from a chloride ion, a bromide ion and an iodide ion. The method for producing the lyophilized preparation comprises formulating the amphoteric cephem-based antibiotic with the halide ion and production by a lyophilization method. The method for stabilizing the lyophilized preparation comprises formulating the amphoteric cephem-based antibiotic with the halide ion.
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