LYOPHILIZED HGF PREPARATION - Patent Pending

(12) Patent Application: (11) CA 2375779
ABSTRACT:
Freeze dried preparations containing hepatocyte growth factor (HGF), a stabilizer such as arginine or lysine, sodium chloride and a buffer. These preparations, which are produced from an aqueous solution containing less than 5 mg/mL of HGF and/or to be used in producing an aqueous solution containing less than 5 mg/mL of HGF, are excellent in storage stability.
(72) Inventors (Country): CHIBA, MASATOSHI (Japan)
(73) Owners (Country): MITSUBISHI CHEMICAL CORPORATION (Japan)
(71) Applicants (Country): MITSUBISHI CHEMICAL CORPORATION (Japan)
(74) Agent: FETHERSTONHAUGH & CO.
(45) Issued:
(86) PCT Filing Date: May 31, 2000
(87) PCT Publication Date: Dec. 7 , 2000
(51) International Class (IPC): A61K 47/02
A61K 9/14
A61K 47/18
A61K 38/22
A61K 47/36
Patent Cooperation Treaty (PCT): Yes (85) National Entry: Nov. 29, 2001
(86) PCT Filing number: PCT/JP2000/003506
(87) International publication number: WO2000/072873
(30) Application priority data: Application No. Country Date
11/151769 Japan May 31, 1999
Availability of licence: N/A
Language of filing: English