LYOPHILIZATION CONTAINERS
(12) Patent: (11) CA 1314399
Application Number: (21) 600693
ABSTRACT OF THE DISCLOSURE The invention provides containers useful for freezedrying of biological and other materials which can be advantageously subjected to a lyophilization process, such materials including proteinaceous materials from which moisture is removed in order to preserve the material in a dry, shelfstable form. The present containers allow lyophilization of the contained material with a minimum of time and energy expenditure by forming the material into a frozen shell to increase the surface area of the material and to minimize the thickness of a given quantity of material which is to be lyophilized. In a typical embodiment of the invention, a container is provided with a congruent, flexible core which is inserted into the container to force the material into the space lying between the container and the core. Expansion of the material on freezing acts to deform the flexible core rather than to break the container. The material thus frozen into a shell-like conformation within the container is then subjected to a lyophilization process after removal of the flexible core.
(72) Inventors (Country): HAAST, WILLIAM E. (United States)
(73) Owners (Country): HAAST, WILLIAM E. (United States)
(71) Applicants (Country):
(74) Agent: MCCARTHY TETRAULT LLP
(45) Issued: Mar. 16, 1993
(22) Filed: May 25, 1989
(41) Open to Public Inspection:
(52) Canadian Class (CPC): 62/1
(51) International Class (IPC): F25D 11/00
F25D 31/00
Patent Cooperation Treaty (PCT): No
(30) Application priority data: None
Availability of licence: N/A
Language of filing: English
Votes:34
Comments: 0