Injectio Natarii Norcantharidatis freeze-drying powder injection and its preparation method

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Patent number: CN1557298
Publication date: 2004-12-29
Inventor: XIAO GUANGCHANG (CN); ZHANG YING (CN)
Applicant: XIAO GUANGCHANG (CN)
Classification:
- international: A61K31/365; A61K9/19; A61P35/00
- european:
Application number: CN200410023468 20040210
Priority number(s): CN200410023468 20040210
Abstract of CN1557298
The present invention is freeze dried demethyl sodium cantharidinate powder for injection and its preparation process, and belongs to the field of medicine technology. The freeze dried demethyl sodium cantharidinate powder for injection contains demethyl cantharidin 0.25-70 wt%, sodium hydroxide 0.1-35 wt% and excipient 0-99 wt%. The preparation process includes compounding demethyl cantharidin and sodium hydroxide in liquid compounding tank, adding injection water and heating to dissolve, adding excipient, dissolving and regulating pH value; adding proper amount of carbon for injection, stirring for 30 min for adsorption, filtering to eliminate carbon and sterilize, packing in Schering bottle, and freeze drying to obtain the freeze dried demethyl sodium cantharidinate powder for injection. The medicine is clinically used in treating liver cancer, esophagus cancer, hepatitis, etc.
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