Increasing the sensitivity of asymmetrical flow field-flow fractionation: Slot outlet technique - Analytical Methods & Tools for Lyophilization

Increasing the sensitivity of asymmetrical flow field-flow fractionation: Slot outlet technique
Engineering Village 2
2006 Elsevier Inc.
Accession number: 063910130830

Title: Increasing the sensitivity of asymmetrical flow field-flow fractionation: Slot outlet technique

Authors: Prestel, Harald; Niessner, Reinhard; Panne, Ulrich

Author affiliation: Institute of Hydrochemistry, Technical University of Munich, D-81377 Munich, Germany

Serial title: Analytical Chemistry

Abbreviated serial title: Anal. Chem.

Volume: v 78

Issue: n 18

Issue date: Sep 15 2006

Publication year: 2006

Pages: p 6664-6669

Language: English

ISSN: 0003-2700

CODEN: ANCHAM

Document type: Journal article (JA)

Publisher: American Chemical Society, Columbus, OH 43210-3337, United States

Abstract: A new enrichment approach is described to improve the sensitivity of the asymmetrical flow field-flow fractionation, with and without ICPMS online coupling for elemental detection. For the slot outlet technique, a part of the laminar carrier stream is removed through an additional pump. This allowed an enrichment of the colloidal particles in the separation channel up to a factor of 14. Additional improvements of the separation efficiency permitted us to separate colloids with differences in their molecular masses of only 2 kDa. Different polymer standards, proteins, and synthesized tracer colloids, as well as real samples (wastewater, liquid manure, serums) were used to assess the performance of the new technique. ? 2006 American Chemical Society.

Number of references: 26

Ei main heading: Particles (particulate matter)

Ei controlled terms: Colloids - Fractionation - Coupled circuits - Laminar flow - Proteins

Uncontrolled terms: Elemental detection - Laminar carrier stream - Colloidal particles - Molecular masses

Ei classification codes: 804 Chemical Products Generally - 801.3 Colloid Chemistry - 802.3 Chemical Operations - 713.5 Other Electronic Circuits - 631.1 Fluid Flow, General - 804.1 Organic Compounds

Treatment: Theoretical (THR)

DOI: 10.1021/ac060259l

Database: Compendex

Compilation and indexing terms, ? 2006 Elsevier Inc. All rights reserved
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