Hydroxycamptothecin liposome and its preparation
Patent Number: CN1582932
Publication date: 2005-02-23
Inventor(s): FENG JIANFANG [CN]; ZHANG LELE [CN]; ZHU LIN [CN]
Applicant(s): SHANGHAI MEDICAL INDUSTRY INST [CN]
Requested Patent: CN1582932
Application Number: CN200410024795 20040531
Priority Number(s): CN200410024795 20040531
IPC Classification: A61K31/475; A61K9/127; A61P35/00
Abstract
A hydroxy camptothecin lipid used for preparing freeze-dried powder injection is prepared from hydroxy camptothecin, phosphatide or cholesterine through dissolving them in organic solvent, spinning evaporating at 40-70 deg.C to become film, adding the buffering liquid containing surfactant, cold storing for hydrating, and stirring.
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