Freeze-dried hepatitis A attenuated live vaccine and its stabilizer

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Patent number: US6884422
Publication date: 2005-04-26
Inventor: LIU JINGYE (CN); WANG PENGFU (CN); LI GUANGPU (CN); XIE BAOSHENG (CN); SONG ZONGMING (CN); LI SHUYAN (CN); LIU JING (CN); YU YING (CN); ZHANG XIZHEN GUANGPU (CN); LIANG BEN (CN); LIU LINGJIU (CN); WANG WEI (CN); ZHANG LING (CN); XUE YONG (CN); LI JING (CN); LI YUHONG (CN); LIN HUI (CN); WAN ZONGJU (CN)
Applicant: CHANGCHUN INST OF BIOLOG PRODU (CN)
Classification:
- international: A61K39/29; A61K39/245; C12N13/00; C12N7/00
- european: A61K9/19; A61K39/29
Application number: US20010807783 20010601
Priority number(s): WO1999CN00157 19991010; CN19980120633 19981019
Abstract of US6884422
The present invention relates to hepatitis A vaccine, especially to a lyophilized attenuated hepatitis A vaccine which can be stored at ambient temperature for extended periods of time, and to a method for producing the same. The present invention further relates to a stabilizer for lyophilized live vaccine and its use in improving thermostability of lyophilized live vaccine during lyophilization processing and storage period after lyophilization.
Data supplied from the esp@cenet database - Worldwi