Freeze-Drying/Lyophilization of Pharmaceutical and Biological Products (Drugs and the Pharmaceutical Sciences: a Series of Textbooks and Monographs)

Freeze-Drying/Lyophilization of Pharmaceutical and Biological Products (Drugs and the Pharmaceutical Sciences: a Series of Textbooks and Monographs)
by Louis Rey (Editor), Joan C. May (Editor)
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"In their 1906 paper to the Academie des Sciences in Paris (almost a century ago), Bordas and d'Arsonval [1] demonstrated for the first time that..." (more)
SIPs: formulations containing dextran, dried biological products, dextran protons, protein chemical potential, occluded moisture (more)
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Edition: Hardcover
Editorial Reviews
From Book News, Inc.
The technology of freeze-drying first gained wide application in the food industry, but recent technological advances means that there are now important uses of freeze-drying (or lyophilization) in the pharmaceutical industry because of the increasing promise of stability of product at the molecular level throughout the entire manufacturing process. Profiling the state of the technology, Rey (a former Head of Corporate Research and Development, Nestle, Switzerland) and May (director, Laboratory of Analytical Chemistry, Center for Biologics Evaluation and Research of the Food and Drug Administration) collect 22 papers profiling a range of research findings and applications, including issues of characterization, equipment, and process validation.Copyright ? 2004 Book News, Inc., Portland, OR
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Product Details
Hardcover: 600 pages
Publisher: Marcel Dekker; 2nd Rev&Ex edition (January 1, 2004)
Language: English
ISBN: 0824748689
Product Dimensions: 9.3 x 6.4 x 1.3 inches
Shipping Weight: 2.1 pounds. (View shipping rates and policies)
Amazon.com Sales Rank: #146,179 in Books
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First Sentence:
In their 1906 paper to the Academie des Sciences in Paris (almost a century ago), Bordas and d'Arsonval [1] demonstrated for the first time that it was possible to dry a delicate product from the frozen state under moderate vacuum. Read the first page
Statistically Improbable Phrases (SIPs): (learn more)
formulations containing dextran, dried biological products, dextran protons, protein chemical potential, occluded moisture, anhydrous phosphorus pentoxide, portable hygrometer, vapor flow density, desorbable water, primary drying temperature, dextran formulation, shelf temperature profile, vitreous transformation, low temperature thermoluminescence, primary drying time, spectral correlation coefficient, lyophilization stoppers, stabilization during freezing, liquid nitrogen immersion freezing, capillary labyrinth, secondary drying, aerosol challenge test, primary drying rates, spraying columns, freeze drying cycle