FREEZE-DRIED POLYMER DISPERSIONS AND THE USE THEREOF IN PREPARING SUSTAINED-RELEASE PHARMACEUTICAL COMPOSITIONS
(12) Patent Application: (11) CA 2012853
Abstract: FREEZE-DRIED POLYMER DISPERSIONS AND THE USE THEREOF IN PREPARING SUSTAINED-RELEASE PHARMACEUTICAL COMPOSITIONS
Freeze-dried polymer latices, which can be reconstituted in water to give aqueous polymer dispersions having high polymer solids content, are described. The reconstituted polymer dispersions are useful in preparing sustained-release drug formulations, particularly of water-soluble drugs, by the wet granulation method without over wetting.
(72) Inventors (Country): PATEL, CHIMANLAL I. (United States)
MEHRA, DEV K. (United States)
BRIDGES, CLAYTON I. (United States)
(73) Owners (Country): FMC CORPORATION (United States)
(71) Applicants (Country):
(74) Agent: OSLER, HOSKIN & HARCOURT LLP
(45) Issued:
(22) Filed: Mar. 22, 1990
(41) Open to Public Inspection: Sep. 23, 1990
Examination requested: Mar. 22, 1990
(52) Canadian Class (CPC): 167/164 260/213 6/65 400/7010
(51) International Class (IPC): C08J 3/07
C08B 11/20
C08B 3/22
A61K 9/32
A61K 9/36
Patent Cooperation Treaty (PCT): No
(30) Application priority data: Application No. Country Date
327,934 United States Mar. 23, 1989
Availability of licence: N/A
Language of filing: English
Comments: 0
Votes:29