FREEZE DRIED HGF PREPARATIONS

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Patent Number: EP1180368
Publication date: 2002-02-20
Inventor(s): CHIBA M (JP)
Applicant(s): MITSUBISHI CHEM CORP (JP)
Requested Patent: CN1367703
Application Number: EP20000935503 20000531
Priority Number(s): WO2000JP03506 20000531; JP19990151769 19990531
IPC Classification: A61K38/22; A61K9/14; A61K9/19
EC Classification: A61K9/19, A61K38/18D, A61K47/18B
Equivalents: AU5103200, CA2375779, WO0072873
Cited Documents: EP0838221; WO9828007
Abstract
A lyophilized preparation having superior storage stability which comprises a hepatocyte growth factor (HGF), a stabilizing agent such as arginine or lysine, sodium chloride, and a buffering agent, which is prepared from an aqueous solution containing the hepatocyte growth factor at a concentration lower than 5 mg/mL and/or which is used for preparing an aqueous solution containing the hepatocyte growth factor at a concentration lower than 5 mg/mL by redissolution.

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