Dermal application system for amino laevulinic acid - European Patents

Patent number: NZ523798
Publication date: 2005-04-29
Inventor: LEE GEOFFREY; SZEIMIES ROLF-MARKUS
Applicant: PHOTONAMIC GMBH & CO
Classification:
- international: A61K31/197; A61K9/70
- european:
Application number: NZ20010523798 20010713
Priority number(s): DE20001034673 20000717; WO2001EP08131 20010713
Abstract of NZ523798

Disclosed is a dermal application system, comprising a self-adhesive matrix system, wherein the polymer matrix contains crystalline aminolaevulinic acid (ALA), wherein the ALA crystals have a size of less than approximately 200 um. A method for preparing the above application system comprises dissolving freeze-dried Eudragit NE (NE) with acetyl tributyl citrate (ATBC) in acetone, wherein the NE/ATBC ratio is 1:0.5 to 1:2.5, after which ground aminolaevulinic acid with a particle size of less than 200 um is dispersed in the acetone solution and the dispersion is drawn to produce a thin film on a cover foil, and dried for 45 minutes at 60 DEG C.
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