Composition for rapid disintegrating tablet in oral cavity - Patent Pending

United States Patent Application 20050106240
Kind Code A1
Tanaka, Nobukazu ; et al. May 19, 2005
Composition for rapid disintegrating tablet in oral cavity
Abstract
The present invention provides rapid disintegrating tablets in oral cavity having a shortened disintegration time in oral cavity as well as a sufficient hardness with compared to rapid disintegrating tablets of the prior art. The above objective is solved by a composition for rapid disintegrating tablets in oral cavity, wherein components (a) to (c) are contained in such manner that (a) saccharides consisting of a combination of mannitol and xylitol is 40 to 90 parts by weight; (b) the inorganic excipient is 1 to 30 parts by weight; and (c) the disintegrating agent is 5 to 40 parts by weight, provided that the total amount of (a), (b) and (c) is 100 parts by weight.
Inventors: Tanaka, Nobukazu; (Nakaniikawa-gun, JP) ; Nagai, Yoshiro; (Nakaniikawa-gun, JP) ; Kawaguchi, Hiroshi; (Nakaniikawa-gun, JP) ; Fukami, Tadashi; (Nakaniikawa-gun, JP) ; Hosokawa, Terumasa; (Nakaniikawa-gun, JP)
Correspondence Name and Address: OBLON, SPIVAK, MCCLELLAND, MAIER & NEUSTADT, P.C.
1940 DUKE STREET
ALEXANDRIA
VA
22314
US
Assignee Name and Adress: FUJI CHEMICAL INDUSTRY CO., LTD.
Nakaniikawa-gun
JP
Serial No.: 945049
Series Code: 10
Filed: September 21, 2004
U.S. Current Class: 424/464; 514/738
U.S. Class at Publication: 424/464; 514/738
Intern'l Class: A61K 009/20; A61K 031/045