Composition and method for treating lupus nephritis
Composition and method for treating lupus nephritis
United States Patent 7,060,797
O'Toole , et al.
June 13, 2006
Inventors: O'Toole; Margot (Newton, MA); Mounts; William Martin (Andover, MA); Shojaee; Negin (Palo Alto, CA)
Assignee: Wyeth (Madison, NJ)
Appl. No.: 719385
Filed: November 21, 2003
Abstract
The present invention provides novel isolated BFLP0169 polynucleotides and polypeptides encoded by the BFLP0169 polynucleotides. Also provided are the antibodies that immunospecifically bind to a BFLP0169 polypeptide or any derivative (including fusion derivative), variant, mutant or fragment of the BFLP0169 polypeptide, polynucleotide or antibody. The invention additionally provides methods in which the BFLP0169 polypeptide, polynucleotide and antibody are utilized in the detection and treatment of a broad range of pathological states, as well as to other uses.
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