CRYO-PROTECTIVE AGENTS FOR MICROORGANISMS

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CRYO-PROTECTIVE AGENTS FOR MICROORGANISMS
Publication Number: WO/2005/054443 International Application No.: PCT/CA2004/002025
Publication Date: 16.06.2005 International Filing Date: 30.11.2004

Int. Class.: C12N 1/04 (2006.01)
Applicants: AVENTIS PASTEUR LIMITED [CA/CA]; 1755 Steeles Avenue West, Toronto, Ontario M2R 3T4 (CA) (All Except US).
LEE, Tim [CA/CA]; 7 Seneca Hill Drive, Toronto, Ontario M2J 2W1 (CA) (US Only).
Inventor: LEE, Tim [CA/CA]; 7 Seneca Hill Drive, Toronto, Ontario M2J 2W1 (CA).
Agent: YACOOB, Reza; 1755 Steeles Avenue West, Toronto, Ontario M2R 3T4 (CA).
Priority Data: 60/481,734 03.12.2003 US

Abstract:
A lyophilization medium for a microorganism is provided wherein the medium is substantially free of animal-derived products and comprises yeast extract and monosodium glutamate. The lyophilisation medium can be used for cryoprotection of strains of bacteria such as Corynebacterium diphtheriae. Method for preparing a freeze-dried culture of a microorganism using the lyophilization medium, and lyophiles of microorganisms are also provided.