Bromhexine Hydrochloride aseptic freeze-drying formulation for injection and its preparation method

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Patent number: CN1557285
Publication date: 2004-12-29
Inventor: MA XIAOQI (CN)
Applicant: MA XIAOQI (CN)
Classification:
- international: A61K31/137; A61K9/19; A61P11/10
- european:
Application number: CN200410021783 20040205
Priority number(s): CN200410021783 20040205
Abstract of CN1557285
The present invention discloses freeze dried bromhexine hydrochloride preparation for injection and its preparation process. The preparation consists of bromhexine hydrochloride as active component, excipient, acidity regulator and injection water. The preparation process includes preparing clear water solution of water insoluble bromhexine hydrochloride with the acidity regulator, adding excipient and freeze drying. The freeze dried bromhexine hydrochloride preparation has raised sability, high bioavailability, less oxidating degradation, no upset reaction and clinical use convenience.
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