Brilliant bingruilin acetate solid lipid nano particle oral preparation and its preparation method
Patent number: CN1555886
Publication date: 2004-12-22
Inventor: PING QINENG (CN); GUO JIANXIN (CN); WU ZHENGHONG (CN)
Applicant: CHINA UNIV OF PHARMACY (CN)
Classification:
- international: A61K38/22; A61K9/127; A61K9/19; A61P11/08; A61P35/00
- european:
Application number: CN200410013846 20040108
Priority number(s): CN200410013846 20040108
Abstract of CN1555886

An orally applied lipid nanoparticle diameter 20nm-1 microns of leuprorelin acetate in the form of freeze dried powder is prepared from leuprorelin acetate, fatty acid, phosphatide, phosphate buffer liquid containing hydrophilic surfactant and freeze drying protector. Its advantages are durable slow releasing and high biologic utilization rate.
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