Analytical ultracentrifugation eases characterization of bioconjugated nanoparticles
Analytical ultracentrifugation eases characterization of bioconjugated nanoparticles
Engineering Village 2
2006 Elsevier Inc
Accession number: 05379354786
Title: Analytical ultracentrifugation eases characterization of bioconjugated nanoparticles
Authors: Boas, Gary
Serial title: Biophotonics International
Abbreviated serial title: Biophoton Int
Volume: v 12
Issue: n 8
Issue date: August 2005
Publication year: 2005
Pages: p 52-53
Language: English
ISSN: 1081-8693
CODEN: BIINFH
Document type: Journal article (JA)
Publisher: Laurin Publishing Co. Inc., Pittsfield, MA 01202-4949, United States
Abstract: Analytical ultracentrifugation, which eases characterization of bioconjugated nanoparticles, was used to study imaging of gold particles. The investigators demonstrated the efficacy of the technique by characterizing gold nanoparticles conjugated to LaCl, an oligomeric DNA-binding protein. The centrifugal force induces particles to sediment over time, creating a boundary of optical density that moves outward from the center of the instrument. Larger nanoparticles to LaCl were conjugated and significant changes were noted in sedimentation behavior.
Abstract type: (Edited abstract)
Ei main heading: Centrifugation
Ei controlled terms: Nanostructured materials - Gold - Lanthanum compounds - Proteins - Oligomers - Density (optical) - Sedimentation - Imaging techniques
Uncontrolled terms: Ultracentrifugation - Bioconjugated nanoparticles - Centrifugal forces - Gold nanoparticles
Ei classification codes: 802.3 Chemical Operations - 933.1 Crystalline Solids - 547.1 Precious Metals - 804.2 Inorganic Compounds - 804.1 Organic Compounds - 815.1.1 Organic Polymers - 741.1 Light/Optics
Treatment: Theoretical (THR)
Database: Compendex
Compilation and indexing terms, ? 2006 Elsevier Inc. All rights reserved
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