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Lyophilization and Protein Formulation
Aptamers - Protein Synthesis

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Peptide aptamer-mediated inhibition of target proteins by sequestration into agg...

Votes:4 Comments:0
Peptide aptamer-mediated inhibition of target proteins by sequestration into aggresomes May 2006 Evangelia Tomai, Karin Butz, Claudia Lohrey, Fritz von Weizs?cker, Hanswalter Zentgraf, and Felix H READ MORE
http://www.jbc.org/cgi/content/abstract/M604258200v1...

RNA Aptamers Targeting the Cell Death Inhibitor CED-9 Induce Cell Killing in Cae...

Votes:37 Comments:0
RNA Aptamers Targeting the Cell Death Inhibitor CED-9 Induce Cell Killing in Caenorhabditis April 7, 2006 Chonglin Yang, Nieng Yan, Jay Parish, Xiaochen Wang, Yigong Shi, and Ding Xue J. Biol. Ch READ MORE
http://www.jbc.org/cgi/content/abstract/281/14/9137...

Delivery of double-stranded DNA thioaptamers into HIV-1 infected cells for antiv...

Votes:31 Comments:0
Delivery of double-stranded DNA thioaptamers into HIV-1 infected cells for antiviral activity 9 June 2006 Monique R. Fergusona, , Daniel R. Rojoa, Anoma Somasunderamb, Varatharasa Thiviyanathanb, READ MORE
http://www.sciencedirect.com/science...

Liquid chromatography, electrochromatography and capillary electrophoresis appli...

Votes:7 Comments:0
Liquid chromatography, electrochromatography and capillary electrophoresis applications of DNA and RNA aptamers 2 June 2006 Corinne Ravelet, Catherine Grosset and Eric Peyrin Journal of Chromatog READ MORE
http://www.sciencedirect.com/science...

The thrombin binding aptamer GGTTGGTGTGGTTGG forms a bimolecular guanine tetrapl...

Votes:15 Comments:0
The thrombin binding aptamer GGTTGGTGTGGTTGG forms a bimolecular guanine tetraplex 26 May 2006 Mark?ta Fialov?, Jaroslav Kypr and Michaela Vorl?ckov? Biochemical and Biophysical Research Communic READ MORE
http://www.sciencedirect.com/science...

Suppression of receptor-mediated apoptosis by death effecter domain recruiting d...

Votes:29 Comments:0
Suppression of receptor-mediated apoptosis by death effecter domain recruiting domain binding peptide aptamer 19 May 2006 Gab Seok Kima, Young Ae Parka, Yong Seok Choia, Yun-Hee Choib, Hyun Woo Ch READ MORE
http://www.sciencedirect.com/science...

Nucleic acid aptamers and enzymes as sensors

Votes:4 Comments:0
Nucleic acid aptamers and enzymes as sensors Available online 4 May 2006 Naveen K Navani and Yingfu Li Current Opinion in Chemical Biology The function of nucleic acids has been an endless sour READ MORE
http://www.sciencedirect.com/science...

Thermodynamic and Kinetic Characterization of Ligand Binding to the Purine Ribos...

Votes:37 Comments:0
Thermodynamic and Kinetic Characterization of Ligand Binding to the Purine Riboswitch Aptamer Domain Available online 21 April 2006. Sunny D. Gilbert?, Colby D Stoddard?, Sarah J. Wise and Robert READ MORE
http://www.sciencedirect.com/science...

Aptamer therapeutics advance

Votes:32 Comments:0
Aptamer therapeutics advance Available online 18 April 2006. Jennifer F Lee, Gwendolyn M Stovall and Andrew D Ellington Current Opinion in Chemical Biology Aptamers are selected nucleic acid b READ MORE
http://www.sciencedirect.com/science...

Aptamer stationary phase for protein capture in affinity capillary chromatograph...

Votes:7 Comments:0
Aptamer stationary phase for protein capture in affinity capillary chromatography 14 April 2006 Adam C. Connora and Linda B. McGown Journal of Chromatography A Abstract The thrombin-binding DN READ MORE
http://www.sciencedirect.com/science...

Peptide aptamers as guides for small-molecule drug discovery

Votes:21 Comments:0
Peptide aptamers as guides for small-molecule drug discovery April 2006 Ivan C. Baines and Pierre Colas Drug Discovery Today Peptide aptamers are combinatorial protein reagents that bind to tar READ MORE
http://www.sciencedirect.com/science...

Structural Determinants of Conformationally Selective, Prion-binding Aptamers

Votes:20 Comments:0
Structural Determinants of Conformationally Selective, Prion-binding Aptamers March 26, 2004 Natalie M. Sayer, Matthew Cubin, Alexandre Rhie, Marc Bullock, Abdessamad Tahiri-Alaoui, and William Ja READ MORE
http://www.jbc.org/cgi/content/abstract/279/13/13102...

Appetite for Aptamers: MIT and Harvard might lead charge to targeted drug delive...

Votes:34 Comments:0
Appetite for Aptamers: MIT and Harvard might lead charge to targeted drug delivery via nanoparticle-aptamer bioconjugate 2006-01-04 by Jeffrey Bouley Drug Discovery News CAMBRIDGE, Mass.?The Mas READ MORE
http://www.drugdiscoverynews.com/index.php...

Pegaptanib, a targeted anti-VEGF aptamer for ocular vascular disease

Votes:9 Comments:0
Pegaptanib, a targeted anti-VEGF aptamer for ocular vascular disease February, 2006 Eugene W. M. Ng 1, David T. Shima 1, Perry Calias , Emmett T. Cunningham, Jr., David R. Guyer , and Anthony P. A READ MORE
http://www.euchromatin.com/NgEWM01.htm

Nucleic Acid Aptamers for Target Validation and Therapeutic Applications

Votes:4 Comments:0
Nucleic Acid Aptamers for Target Validation and Therapeutic Applications 2005 P. Shannon Pendergrast, H. Nicholas Marsh, Dilara Grate, Judith M. Healy and Martin Stanton Journal of Biomolecular T READ MORE
http://jbt.abrf.org/cgi/content/full/16/3/224

Nanoparticle?aptamer bioconjugates for cancer targeting

Votes:18 Comments:0
Nanoparticle?aptamer bioconjugates for cancer targeting May 2006 Omid C Farokhzad1, ?Jeffrey M Karp?2 & ?Robert Langer Informa Healthcare The combination of targeted drug delivery and controlled READ MORE
http://www.expertopin.com/doi/abs/10.1517/17425247.3.3.311;jsessionid=...

Patterns of Aptamers on Polyelectrolyte Multilayers

Votes:31 Comments:0
Patterns of Aptamers on Polyelectrolyte Multilayers October 2005 Srivatsan Kidambi1, Ilsoon Lee1, and Christina Chan2. (1) Department of Chemical Engineering and Materials Science, Michigan State READ MORE
http://aiche.confex.com/aiche/2005/techprogram/P28104.HTM

Finding the Opportunities in Aptamers

Votes:26 Comments:0
Finding the Opportunities in Aptamers March 2004 Windhover Information Inc. The pharmaceutical industry, it?s fair to say, hasn?t completely gotten over its infatuation with small molecules. But READ MORE
http://www.windhover.com/contents/monthly/exex/e_2004800052.htm

Aptamer selection based on inhibitory activity using an evolution-mimicking algo...

Votes:31 Comments:0
Aptamer selection based on inhibitory activity using an evolution-mimicking algorithm 18 August 2006 Takahisa Nomaa and Kazunori Ikebukuro Biochemical and Biophysical Research Communications Ab READ MORE
http://www.sciencedirect.com/science...

Biomolecular sensor based on fluorescence-labeled aptamer

Votes:25 Comments:0
Biomolecular sensor based on fluorescence-labeled aptamer 15 August 2006 Hiroaki Ozaki, a, , Akifumi Nishihiraa, Masayuki Wakabayashia, Masayasu Kuwaharaa and Hiroaki Sawai Bioorganic & Medicinal READ MORE
http://www.sciencedirect.com/science...

Synthesis of a liposome incorporated 1-carboxyalkylxanthine-phospholipid conjuga...

Votes:39 Comments:0
Synthesis of a liposome incorporated 1-carboxyalkylxanthine-phospholipid conjugate and its recognition by an RNA aptamer 2006 Katie A. Edwardsa and Antje J. Baeumner Talanta Abstract RNA or DN READ MORE
http://www.sciencedirect.com/science...

Selection and analytical applications of aptamers

Votes:14 Comments:0
Selection and analytical applications of aptamers 2006 Camille L.A. Hamula1, a, Jeffrey W. Guthrie1, a, Hongquan Zhanga, Xing-Fang Lia and X. Chris Le TrAC Trends in Analytical Chemistry Abstra READ MORE
http://www.sciencedirect.com/science...

Influence of ionic strength, pH and aptamer configuration for binding affinity t...

Votes:28 Comments:0
Influence of ionic strength, pH and aptamer configuration for binding affinity to thrombin 2006 Tibor Hianik, , Veronika Ostatn?, Michaela Sonlajtnerova and Igor Grman Bioelectrochemistry Abstr READ MORE
http://www.sciencedirect.com/science...

Aptamer:toxin conjugates that specifically target prostate tumor cells

Votes:7 Comments:0
Aptamer:toxin conjugates that specifically target prostate tumor cells 2006 Jun 15 Chu TC, Marks JW 3rd, Lavery LA, Faulkner S, Rosenblum MG, Ellington AD, Levy M. Cancer Res. We have used RNA READ MORE
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi...

Aptamer mediated siRNA delivery

Votes:34 Comments:0
Aptamer mediated siRNA delivery 2006 Jun 1 Chu TC, Twu KY, Ellington AD, Levy M. Nucleic Acids Res. Nucleic acids that bind to cells and are subsequently internalized could prove to be novel de READ MORE
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi...

Tumor targeting by an aptamer

Votes:29 Comments:0
Tumor targeting by an aptamer 2006 Apr Hicke BJ, Stephens AW, Gould T, Chang YF, Lynott CK, Heil J, Borkowski S, Hilger CS, Cook G, Warren S, Schmidt PG. J Nucl Med. Aptamers are small oligonuc READ MORE
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi...

The potential of aptamers as anticoagulants

Votes:5 Comments:0
The potential of aptamers as anticoagulants 2005 Jan Nimjee SM, Rusconi CP, Harrington RA, Sullenger BA. Trends Cardiovasc Med. Useful additional options for anticoagulant therapy have been intr READ MORE
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi...

Engineering Aptamer and SIRNA Based Drug Delivery Systems Using Polyelectrolyte ...

Votes:17 Comments:0
Engineering Aptamer and SIRNA Based Drug Delivery Systems Using Polyelectrolyte Multilayer Films 13 November 2006 Srivatsan Kidambi1, Ilsoon Lee, and Christina Chan2. (1) Department of Chemical E READ MORE
http://aiche.confex.com/aiche/2006/techprogram/P66701.HTM

Cancer nanotechnology: drug encapsulated nanoparticle-aptamer bioconjugates for ...

Votes:12 Comments:0
Cancer nanotechnology: drug encapsulated nanoparticle-aptamer bioconjugates for targeted delivery to prostate cancer cells November 2005 O.C. Farokhzad12, J. Cheng2, B. Teply2, A. Khademhosseini2, READ MORE
http://ex2.excerptamedica.com/ciw-05ecco/abstracts/index.cfm...

Functional DNA nanotechnology: emerging applications of DNAzymes and aptamers

Votes:29 Comments:0
Functional DNA nanotechnology: emerging applications of DNAzymes and aptamers 2006 Oct 20 Lu Y, Liu J. Department of Chemistry, Beckman Institute for Advanced Science and Technology, University READ MORE
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi...

In vitro selection of DNA aptamer against abrin toxin and aptamer-based abrin di...

Votes:5 Comments:0
In vitro selection of DNA aptamer against abrin toxin and aptamer-based abrin direct detection 2006 Oct 18 Tang J, Yu T, Guo L, Xie J, Shao N, He Z. Beijing Institute of Pharmacology and Toxicol READ MORE
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi...

The effect of electrochemical functionalization of Ti-alloy surfaces by aptamer-...

Votes:37 Comments:0
The effect of electrochemical functionalization of Ti-alloy surfaces by aptamer-based capture molecules on cell adhesion 2007 Jan Guo KT, Scharnweber D, Schwenzer B, Ziemer G, Wendel HP. Departm READ MORE
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi...

Codeine-binding RNA aptamers and rapid determination of their binding constants ...

Votes:7 Comments:0
Codeine-binding RNA aptamers and rapid determination of their binding constants using a direct coupling surface plasmon resonance assay 2006 Oct 11 Win MN, Klein JS, Smolke CD. Division of Chemi READ MORE
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi...

Single-chain antibodies against DNA aptamers for use as adapter molecules on DNA...

Votes:10 Comments:0
Single-chain antibodies against DNA aptamers for use as adapter molecules on DNA tile arrays in nanoscale materials organization 2006 Sep 21 Li H, LaBean TH, Kenan DJ. Department of Pathology, D READ MORE
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi...

DNA Aptamers That Bind to MUC1 Tumour Marker: Design and Characterization of MUC...

Votes:5 Comments:0
DNA Aptamers That Bind to MUC1 Tumour Marker: Design and Characterization of MUC1-Binding Single-Stranded DNA Aptamers 2006 Ferreira CS, Matthews CS, Missailidis S. Chemistry Department, The Ope READ MORE
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi...

Selection and characterization of RNA aptamers to the RNA-dependent RNA polymera...

Votes:38 Comments:0
Selection and characterization of RNA aptamers to the RNA-dependent RNA polymerase from foot-and-mouth disease virus 2006 Oct 3 Ellingham M, Bunka DH, Rowlands DJ, Stonehouse NJ. Institute of Mo READ MORE
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi...

DNA and RNA aptamers: from tools for basic research towards therapeutic applicat...

Votes:13 Comments:0
DNA and RNA aptamers: from tools for basic research towards therapeutic applications 2006 Sep Ulrich H, Trujillo CA, Nery AA, Alves JM, Majumder P, Resende RR, Martins AH. Departamento de Bioqui READ MORE
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi...

Analysis of the evolution of the thrombin-inhibiting DNA aptamers using a geneti...

Votes:8 Comments:0
Analysis of the evolution of the thrombin-inhibiting DNA aptamers using a genetic algorithm 2006 Oct 3 Ikebukuro K, Yoshida W, Noma T, Sode K. Department of Life Science and Biotechnology, Tokyo READ MORE
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi...

Aptamers targeted to an RNA hairpin show improved specificity compared to that o...

Votes:40 Comments:0
Aptamers targeted to an RNA hairpin show improved specificity compared to that of complementary oligonucleotides 2006 Oct 3 Darfeuille F, Reigadas S, Hansen JB, Orum H, Di Primo C, Toulme JJ. IN READ MORE
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi...

RNA aptamers binding the double-stranded RNA-binding domain

Votes:16 Comments:0
RNA aptamers binding the double-stranded RNA-binding domain 2006 Sep 25 Hallegger M, Taschner A, Jantsch MF. Department of Chromosome Biology, Max F. Perutz Laboratories, University of Vienna, V READ MORE
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi...

Non-SELEX: selection of aptamers without intermediate amplification of candidate...

Votes:34 Comments:0
Non-SELEX: selection of aptamers without intermediate amplification of candidate oligonucleotides 2006 Maxim V Berezovski, Michael U Musheev, Andrei P Drabovich, Julia V Jitkova and Sergey N Krylo READ MORE
http://www.nature.com/nprot/journal/v1/n3/full/nprot.2006.200.html

Fabrication and characterization of RNA aptamer microarrays for the study of pro...

Votes:23 Comments:0
Fabrication and characterization of RNA aptamer microarrays for the study of protein-aptamer interactions with SPR imaging 2006 Nov 27 Li Y, Lee HJ, Corn RM Nucleic Acids Res. RNA microarrays w READ MORE
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi...

In vitro selection of DNA aptamer against abrin toxin and aptamer-based abrin di...

Votes:6 Comments:0
In vitro selection of DNA aptamer against abrin toxin and aptamer-based abrin direct detection 2006 Oct 18 Tang J, Yu T, Guo L, Xie J, Shao N, He Z Biosens Bioelectron. Abrin toxin as the target READ MORE
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi...

RiboaptDB: A Comprehensive Database of Ribozymes and Aptamers

Votes:34 Comments:0
RiboaptDB: A Comprehensive Database of Ribozymes and Aptamers 2006 Sep 26 Thodima V, Pirooznia M, Deng Y BMC Bioinformatics. ABSTRACT : BACKGROUND : Catalytic RNA molecules are called ribozymes. READ MORE
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi...

Electrochemical detection of 17beta-estradiol using DNA aptamer immobilized gold...

Votes:9 Comments:0
Electrochemical detection of 17beta-estradiol using DNA aptamer immobilized gold electrode chip 2006 Nov 20 Kim YS, Jung HS, Matsuura T, Lee HY, Kawai T, Gu MB Biosens Bioelectron. An electroch READ MORE
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi...

Ligand-regulated Peptide Aptamers that Inhibit the 5'-AMP-activated Protein Kina...

Votes:4 Comments:0
Ligand-regulated Peptide Aptamers that Inhibit the 5'-AMP-activated Protein Kinase 2006 Jul 26 Miller RA, Binkowski BF, Belshaw PJ J Mol Biol. In an effort to extend the peptide aptamer approac READ MORE
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi...

Proteins modified with DNAzymes or aptamers act as biosensors or biosensor label...

Votes:18 Comments:0
Proteins modified with DNAzymes or aptamers act as biosensors or biosensor labels 2006 Nov 10 Shlyahovsky B, Li D, Katz E, Willner I Biosens Bioelectron. Hybrid systems composed of a glucose oxi READ MORE
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi...

An RNA aptamer that interferes with the DNA binding of the HSF transcription act...

Votes:31 Comments:0
An RNA aptamer that interferes with the DNA binding of the HSF transcription activator 7 August 2006 Xiaoching Zhao, Hua Shi, Aarti Sevilimedu, Nicole Liachko, Hillary C. M. Nelson1 and John T. Li READ MORE
http://nar.oxfordjournals.org/cgi/content/full/34/13/3755...

NMR structures of double loops of an RNA aptamer against mammalian initiation fa...

Votes:26 Comments:0
NMR structures of double loops of an RNA aptamer against mammalian initiation factor 4A 1 February 2005 Taiichi Sakamoto, Akihiro Oguro, Gota Kawai1, Takashi Ohtsu and Yoshikazu Nakamura Nucleic READ MORE
http://nar.oxfordjournals.org/cgi/content/full/33/2/745...

Fabrication and characterization of RNA aptamer microarrays for the study of pro...

Votes:21 Comments:0
Fabrication and characterization of RNA aptamer microarrays for the study of protein?aptamer interactions with SPR imaging November 27, 2006 Yuan Li, Hye Jin Lee and Robert M. Corn Nucleic Acids READ MORE
http://nar.oxfordjournals.org/cgi/content/full/gkl738v1...

Aptamer mediated siRNA delivery

Votes:15 Comments:0
Aptamer mediated siRNA delivery 1 June 2006 Ted C. Chu, Karen Y. Twu, Andrew D. Ellington and Matthew Levy Nucleic Acids Research Nucleic acids that bind to cells and are subsequently internali READ MORE
http://nar.oxfordjournals.org/cgi/content/full/34/10/e73...

Application of locked nucleic acids to improve aptamer in vivo stability and tar...

Votes:29 Comments:0
Application of locked nucleic acids to improve aptamer in vivo stability and targeting function 27 October 2004 Kathrin S. Schmidt, Sandra Borkowski1, Jens Kurreck, Andrew W. Stephens1, Rolf Bald, READ MORE
http://nar.oxfordjournals.org/cgi/content/full/32/19/5757...

H1 RNA polymerase III promoter-driven expression of an RNA aptamer leads to high...

Votes:24 Comments:0
H1 RNA polymerase III promoter-driven expression of an RNA aptamer leads to high-level inhibition of intracellular protein activity 19 July 2006 Jing Mi1, Xiuwu Zhang2, Zahid N Rabbani3, Yingmiao READ MORE
http://nar.oxfordjournals.org/cgi/content/full/34/12/3577...

A modular DNA signal translator for the controlled release of a protein by an ap...

Votes:37 Comments:0
A modular DNA signal translator for the controlled release of a protein by an aptamer 17 March 2006 Stefan Beyer and Friedrich C. Simmel Nucleic Acids Research Owing to the intimate linkage of READ MORE
http://nar.oxfordjournals.org/cgi/content/full/34/5/1581...

A hepatitis C virus (HCV) internal ribosome entry site (IRES) domain III?IV-targ...

Votes:32 Comments:0
A hepatitis C virus (HCV) internal ribosome entry site (IRES) domain III?IV-targeted aptamer inhibits translation by binding to an apical loop of domain IIId 28 January 2005 Kunio Kikuchi1,2, Taku READ MORE
http://nar.oxfordjournals.org/cgi/content/full/33/2/683...

A new modified thrombin binding aptamer containing a 5'?5' inversion of polarity...

Votes:31 Comments:0
A new modified thrombin binding aptamer containing a 5'?5' inversion of polarity site December 1, 2006 Luigi Martino, Ada Virno1, Antonio Randazzo1, Antonella Virgilio1, Veronica Esposito1, Conce READ MORE
http://nar.oxfordjournals.org/cgi/content/full/34/22/6653
Aptamers - Protein Synthesis
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